Protein Modification Reagents
Medchemexpress LLC Mal-PEG2-NHS ester | 1433997-01-3 | MFCD24539465 | 98.6% | 354.31 | C15H18N2O8 | 5 G
Mal-PEG2-NHS ester is a non-cleavable antibody-drug conjugate (ADC) linker that contains a maleimide thiol-reactive group, a two-unit polyethylene glycol (PEG2) spacer, and an N-hydroxysuccinimide (NHS) ester for amine coupling. It is supplied as a viscous, colorless to off-white liquid and is used for thiol-to-amine bioconjugation in ADC construction and other protein labeling applications.
- Non-cleavable maleimide-NHS bifunctional linker.
- 2-unit PEG spacer improves solubility and reduces aggregation.
- Thiol-reactive maleimide enables cysteine conjugation.
- NHS ester enables coupling to primary amines.
- High purity (≈98.6%) suitable for research applications.
- Available in multiple pack sizes, including 5 G.
- Recommended storage: -20°C (pure), -80°C (in solvent) per supplier storage instructions.
Creative Pegworks mPEG-SCM, MW 2000, 1 g
mPEG-SCM is one type of mPEG-NHS reagents. There is a methylene (CH2) linkage between PEG and the NHS ester.
Medchemexpress LLC DSPE-PEG-Folate | 1236288-25-7 | MFCD07107414 | 95.7% | 5000 | 5 MG
DSPE-PEG-Folate (MW 5000) is a PEGylated phospholipid in which DSPE is linked to a polyethylene glycol chain terminated with folic acid. It is designed to incorporate into liposomes or nanoparticle surfaces to present folate ligands for receptor-mediated targeting and uptake, and is used in targeted drug delivery, imaging, and nanoparticle functionalization in research settings.
- Facilitates folate-receptor mediated targeting.
- Integrates into lipid bilayers and can form micelles.
- Average molecular weight of 5000 for extended circulation properties.
- High purity (≈95.7%) suitable for research applications.
- Stable as a powder when stored at -20°C for long-term storage.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG20-CH2CH2COOH | 1 g | CAS 1952360-93-8 | MDL MFCD21363316
Fmoc-NH-PEG20-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 1 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1952360-93-8
- MDL: MFCD21363316
- InChIKey: YIKBHNBKAGGRHQ-UHFFFAOYSA-N
- Molecular Weight: 1192.397
- Molecular Formula: C58H97NO24
- Purity: ≥95%
- Container Type: 15 mL HDPE
- Pack Size: 1 g
- Net Weight: 1 g
- Gross Weight: 7.8 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-henicosaoxa-4-azaheptahexacontan-67-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O
Medchemexpress LLC Dopamine-PEG-N3 MW 25mg
Dopamine-PEG-N3 (MW 2000) (Dopamine-PEG-Azide (MW 2000)) is a compound composed of dopamine PEG segments and an azide group (-N3) Dopamine-PEG-N3 (MW 2000) can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials Dopamine-PEG-N3 (MW 2000) is a click chemistry reagent It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group
Medchemexpress LLC 3,6,9,15,18,21-Hexaoxa-12-azatricosane-1,23-diol | 63721-14-2 | 98.0% | C16H35NO8 | 500 MG
NH-bis-PEG4 is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These compounds employ the intracellular ubiquitin-proteasome system to specifically degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Leverages the ubiquitin-proteasome system
- Specifically degrades target proteins
Medchemexpress LLC Biotin-PEG-azide | 956494-20-5 | 98.7% | 2000.00 | 100 MG
Biotin-PEG-azide (MW 2000) is a biotinylated polyethylene glycol derivative with a terminal azide functional group. Supplied as a powder with an average molecular weight of 2000, it is designed for use in bioconjugation workflows such as copper-catalyzed azide-alkyne cycloaddition and for affinity labeling or capture of biomolecules. Manufacturer datasheets provide purity, storage, and handling details.
Medchemexpress LLC Bis-PEG4-PFP ester | 1314378-12-5 | 97.0% | 500 MG
Bis-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- PROTACs consist of two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase.
- The other ligand targets the protein of interest.
- PROTACs utilize the intracellular ubiquitin-proteasome system.
- Selectively degrade target proteins.
Medchemexpress LLC Mal-amido-PEG6-acid | 1334177-79-5 | 99.3% | 50 MG
Mal-amido-PEG6-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules are designed to exploit the intracellular ubiquitin-proteasome system, selectively degrading target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Enables targeted protein degradation
- Facilitates connection of E3 ubiquitin ligase and target protein ligands
Medchemexpress LLC Mal-PEG5-NHS ester | 1807537-42-3 | 99.0% | 50 MG
Mal-PEG5-NHS ester is an alkyl/ether and PEG-based PROTAC linker. It is utilized in the synthesis of Proteolysis-targeting chimeras (PROTACs), which are compounds designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl/ether and PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Designed to selectively degrade target proteins
Medchemexpress LLC NH-bis(C2-PEG2-NH-Boc) | 2182601-69-8 | 50 MG
NH-bis(C2-PEG2-NH-Boc) is a laboratory chemical identified for use in the manufacture of substances. This compound is a stable liquid with a molecular formula of C22H45N3O8 and a molecular weight of 479.61.
- Identified for use as a laboratory chemical
- Stable under recommended storage conditions
- Pure form storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Shipping at room temperature if less than 2 weeks
- Appearance: liquid
- Boiling point/range: 577.0±50.0 °C at 760 mmHg
- Relative density: 1.064 g/cm³
eMolecules 557756-85-1 | Fmoc-NH-PEG4-CH2CH2COOH | Ambeed | MFCD06656472 | 487.549 | C26H33NO8 | 98.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 552521111
Fmoc-NH-PEG4-CH2CH2COOH | Ambeed | 557756-85-1 | MFCD06656472 | 487.549 | C26H33NO8 | 98.000 | OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 25g | 552521111